Research statistics
Pinealon research: publications and trials
At a glance
Publications, all years
22
Since 2008
Publications in 2026 so far
0
Through November 1, 2026
Human clinical research
22.7%
5 of 22 classified
Registered clinical trials
0
ClinicalTrials.gov
Randomized controlled trials
0
Publications reporting an RCT in people
Systematic reviews and meta-analyses
0
Preclinical studies
68.2%
12 animal · 3 in vitro · 0 computational
Records that only mention it
2
Not counted above
Status in the library: Research only. Groups: Short peptide bioregulators, Cognitive and neurological peptides, Longevity and mitochondrial peptides.
What to keep in mind
- Fewer than three randomized controlled trials are indexed.
- Fewer than 25 publications are indexed, so year-to-year changes are not meaningful.
Publications by year
Pinealon publications by year and evidence
Show the data
| Year | Human clinical research | Preclinical (animal, in vitro, computational) | Reviews and meta-analyses | Total |
|---|---|---|---|---|
| 2008 | 0 | 2 | 0 | 2 |
| 2011 | 0 | 4 | 0 | 4 |
| 2012 | 2 | 2 | 0 | 4 |
| 2013 | 0 | 1 | 1 | 2 |
| 2014 | 0 | 2 | 0 | 2 |
| 2015 | 2 | 1 | 0 | 3 |
| 2016 | 1 | 0 | 0 | 1 |
| 2019 | 0 | 1 | 0 | 1 |
| 2020 | 0 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 0 | 1 |
Study types
| Animal study | 12 |
|---|---|
| Other clinical trial | 4 |
| In vitro study | 3 |
| Review | 2 |
| Observational human study | 1 |
Research areas
From MeSH major topics. A paper can be in several areas.
| Neurological and mental health | 12 |
|---|---|
| Longevity and aging | 10 |
| Cognitive health | 3 |
| Cardiovascular | 1 |
| Dermatology | 1 |
| Endocrinology | 1 |
| Immune system | 1 |
| Reproductive and sexual health | 1 |
Registered clinical trials
A registration is not a result.
No registered trials.
Human trials and evidence reviews
Meta-analyses, systematic reviews and trials in people, newest first.
- [Comparative analysis of different methods of geroprotective].
Advances in gerontology = Uspekhi gerontologii · January 1, 2016 · Other clinical trial · cited 0 times
PMID 28539017 · Human clinical research
- [Assessment of work ability index in evaluation of small peptides geroprotective effect].
Advances in gerontology = Uspekhi gerontologii · January 1, 2015 · Other clinical trial · cited 0 times
PMID 28509489 · Human clinical research
- [EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].
Advances in gerontology = Uspekhi gerontologii · January 1, 2015 · Other clinical trial · cited 1 times
PMID 26390612 · Human clinical research
- [The peptide correction of neurotic disorders among professional truck-drivers].
Advances in gerontology = Uspekhi gerontologii · January 1, 2012 · Other clinical trial · cited 2 times
PMID 23734521 · Human clinical research
Most cited
By OpenAlex citation count. Citations measure attention, not quality or correctness.
- Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA.
Biochemistry. Biokhimiia · November 1, 2011 · In vitro study · cited 64 times
PMID 22117547 · DOI 10.1134/s0006297911110022 · In vitro studies
- Optimization of Jiuzao protein hydrolysis conditions and antioxidant activity in vivo of Jiuzao tetrapeptide Asp-Arg-Glu-Leu by elevating the Nrf2/Keap1-p38/PI3K-MafK signaling pathway.
Food & function · June 1, 2021 · Animal study · cited 51 times
PMID 33876788 · DOI 10.1039/d0fo02852e · Animal studies
- Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.
International journal of clinical and experimental medicine · April 6, 2012 · Animal study · cited 27 times · open access
PMID 22567179 · Animal studies
- Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes.
Rejuvenation research · October 6, 2011 · Animal study · cited 17 times
PMID 21978084 · DOI 10.1089/rej.2011.1172 · Animal studies
- EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease.
Molecules (Basel, Switzerland) · December 31, 2020 · Review · cited 13 times · open access
PMID 33396470 · DOI 10.3390/molecules26010159 · Reviews and meta-analyses
Latest publications
- Short Peptides Protect Fibroblast-Derived Induced Neurons from Age-Related Changes.
International journal of molecular sciences · October 22, 2024 · In vitro study · cited 3 times · open access
PMID 39518916 · DOI 10.3390/ijms252111363 · In vitro studies
- Optimization of Jiuzao protein hydrolysis conditions and antioxidant activity in vivo of Jiuzao tetrapeptide Asp-Arg-Glu-Leu by elevating the Nrf2/Keap1-p38/PI3K-MafK signaling pathway.
Food & function · June 1, 2021 · Animal study · cited 51 times
PMID 33876788 · DOI 10.1039/d0fo02852e · Animal studies
- EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease.
Molecules (Basel, Switzerland) · December 31, 2020 · Review · cited 13 times · open access
PMID 33396470 · DOI 10.3390/molecules26010159 · Reviews and meta-analyses
- Role of Mono- and Divalent Ions in Peptide Glu-Asp-Arg-DNA Interaction.
The journal of physical chemistry. B · February 22, 2019 · Animal study · cited 5 times
PMID 30762356 · DOI 10.1021/acs.jpcb.8b10359 · Animal studies
- [Comparative analysis of different methods of geroprotective].
Advances in gerontology = Uspekhi gerontologii · January 1, 2016 · Other clinical trial · cited 0 times
PMID 28539017 · Human clinical research
- [Assessment of work ability index in evaluation of small peptides geroprotective effect].
Advances in gerontology = Uspekhi gerontologii · January 1, 2015 · Other clinical trial · cited 0 times
PMID 28509489 · Human clinical research
- [EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].
Advances in gerontology = Uspekhi gerontologii · January 1, 2015 · Other clinical trial · cited 1 times
PMID 26390612 · Human clinical research
- [Pinealon and Cortexin influence on behavior and neurochemical processes in 18-month aged rats within hypoxia and hypothermia].
Advances in gerontology = Uspekhi gerontologii · January 1, 2015 · Animal study · cited 0 times
PMID 28509493 · Animal studies
- Short peptides stimulate serotonin expression in cells of brain cortex.
Bulletin of experimental biology and medicine · May 1, 2014 · Animal study · cited 9 times
PMID 24909721 · DOI 10.1007/s10517-014-2496-y · Animal studies
- [Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].
Advances in gerontology = Uspekhi gerontologii · January 1, 2014 · Animal study · cited 3 times
PMID 25051764 · Animal studies
How this is counted
PubMed records matched by the names below, counted when the peptide is in the title, indexed by MeSH, or confirmed from the abstract. The exact query can be rerun on Europe PMC. Methodology
Search terms: EDR peptide; Pinealon
((TITLE_ABS:"EDR peptide" OR CHEM:"EDR peptide") OR (TITLE_ABS:"Pinealon" OR CHEM:"Pinealon")) AND SRC:MED
Cite this page
Peptide Library. (2026, November 2). Pinealon research statistics (Version weekly-2026-11-01) [Statistic]. Peptide Library. https://bestpeptidecalculator.app/research/peptides/pinealon