Peptide LibraryResearch statistics
Triptorelin research: publications and trials
At a glance
Publications, all years
1,670
Since 1980
Publications in 2026 so far
29
Through November 1, 2026
Human clinical research
69.6%
1,152 of 1,655 classified
Registered clinical trials
200
ClinicalTrials.gov
Randomized controlled trials
270
Publications reporting an RCT in people
Systematic reviews and meta-analyses
9
Preclinical studies
25.3%
303 animal · 106 in vitro · 10 computational
Records that only mention it
830
Not counted above
Status in the library: FDA-approved. 15 publications are not yet classified by study type.
What to keep in mind
- Some completed trials have neither posted results nor a linked results publication.
Publications by year
Triptorelin publications by year and evidence
Show the data
| Year | Human clinical research | Preclinical (animal, in vitro, computational) | Reviews and meta-analyses | Other and not yet classified | Total |
|---|---|---|---|---|---|
| 1980 | 2 | 4 | 0 | 0 | 6 |
| 1981 | 10 | 7 | 0 | 0 | 17 |
| 1982 | 7 | 3 | 0 | 0 | 10 |
| 1983 | 5 | 5 | 0 | 0 | 10 |
| 1984 | 17 | 10 | 0 | 0 | 27 |
| 1985 | 12 | 17 | 0 | 0 | 29 |
| 1986 | 25 | 6 | 1 | 0 | 32 |
| 1987 | 17 | 11 | 0 | 3 | 31 |
| 1988 | 32 | 11 | 2 | 4 | 49 |
| 1989 | 29 | 13 | 1 | 1 | 44 |
| 1990 | 22 | 13 | 0 | 1 | 36 |
| 1991 | 26 | 12 | 0 | 0 | 38 |
| 1992 | 30 | 14 | 0 | 0 | 44 |
| 1993 | 42 | 13 | 0 | 0 | 55 |
| 1994 | 44 | 7 | 1 | 1 | 53 |
| 1995 | 36 | 3 | 0 | 0 | 39 |
| 1996 | 38 | 8 | 0 | 0 | 46 |
| 1997 | 27 | 5 | 0 | 1 | 33 |
| 1998 | 34 | 10 | 1 | 0 | 45 |
| 1999 | 26 | 7 | 0 | 0 | 33 |
| 2000 | 35 | 7 | 1 | 1 | 44 |
| 2001 | 27 | 13 | 1 | 3 | 44 |
| 2002 | 19 | 14 | 1 | 1 | 35 |
| 2003 | 24 | 7 | 2 | 2 | 35 |
| 2004 | 23 | 12 | 1 | 3 | 39 |
| 2005 | 24 | 10 | 4 | 0 | 38 |
| 2006 | 30 | 9 | 1 | 2 | 42 |
| 2007 | 24 | 3 | 1 | 0 | 28 |
| 2008 | 25 | 14 | 0 | 1 | 40 |
| 2009 | 25 | 8 | 1 | 0 | 34 |
| 2010 | 18 | 7 | 4 | 1 | 30 |
| 2011 | 21 | 7 | 1 | 3 | 32 |
| 2012 | 33 | 12 | 0 | 1 | 46 |
| 2013 | 21 | 5 | 1 | 1 | 28 |
| 2014 | 19 | 10 | 1 | 1 | 31 |
| 2015 | 35 | 12 | 4 | 1 | 52 |
| 2016 | 30 | 10 | 4 | 0 | 44 |
| 2017 | 16 | 9 | 3 | 1 | 29 |
| 2018 | 28 | 12 | 5 | 1 | 46 |
| 2019 | 26 | 8 | 2 | 0 | 36 |
| 2020 | 31 | 7 | 0 | 0 | 38 |
| 2021 | 24 | 7 | 2 | 1 | 34 |
| 2022 | 19 | 7 | 1 | 2 | 29 |
| 2023 | 19 | 4 | 4 | 0 | 27 |
| 2024 | 30 | 7 | 0 | 1 | 38 |
| 2025 | 27 | 11 | 4 | 3 | 45 |
| 2026 (to date) | 18 | 8 | 3 | 0 | 29 |
Study types
| Other clinical trial | 418 |
|---|---|
| Observational human study | 309 |
| Animal study | 303 |
| Randomized controlled trial | 270 |
| Case report | 155 |
| In vitro study | 106 |
| Review | 49 |
| Editorial, letter or other | 26 |
| Not yet classified | 15 |
| Computational study | 10 |
| Systematic review | 5 |
| Meta-analysis | 4 |
Research areas
From MeSH major topics. A paper can be in several areas.
| Reproductive and sexual health | 1,028 |
|---|---|
| Endocrinology | 843 |
| Oncology | 578 |
| Neurological and mental health | 163 |
| Dermatology | 91 |
| Musculoskeletal | 71 |
| Immune system | 41 |
| Metabolic health | 41 |
| Gastrointestinal | 32 |
| Cardiovascular | 29 |
| Obesity and weight management | 25 |
| Longevity and aging | 15 |
Registered clinical trials
38 of 87 trials completed at least a year before the cutoff have neither posted results nor a linked results publication. A registration is not a result.
Completed: 90 · Unknown status: 56 · Recruiting: 27 · Terminated: 12 · Active, not recruiting: 8 · Withdrawn: 5 · Not yet recruiting: 2
Early phase 1: 1 · Phase not applicable: 47 · Phase 1: 2 · Phase 1 / Phase 2: 2 · Phase 2: 38 · Phase 2 / Phase 3: 9 · Phase 3: 54 · Phase 4: 47
The 50 most recently started of 200 trials.
Human trials and evidence reviews
Meta-analyses, systematic reviews and trials in people, newest first.
- Effects of fixed-time artificial insemination using triptorelin on the reproductive performance of pigs: a meta-analysis.
Animal : an international journal of animal bioscience · December 20, 2019 · Meta-analysis · cited 7 times · open access
PMID 31858952 · DOI 10.1017/s1751731119003008 · Reviews and meta-analyses
- GnRH analog is ineffective in increasing adult height in girls with puberty onset after 7 years of age: a systematic review and meta-analysis.
European journal of endocrinology · December 1, 2018 · Meta-analysis · cited 28 times
PMID 30324797 · DOI 10.1530/eje-18-0473 · Reviews and meta-analyses
- Meta-Analysis of Paediatric Patients with Central Precocious Puberty Treated with Intramuscular Triptorelin 11.25 mg 3-Month Prolonged-Release Formulation .
Hormone research in paediatrics · March 23, 2017 · Meta-analysis · cited 23 times
PMID 28334719 · DOI 10.1159/000456545 · Reviews and meta-analyses
- Administration of single-dose GnRH agonist in the luteal phase in ICSI cycles: a meta-analysis.
Reproductive biology and endocrinology : RB&E · September 8, 2010 · Meta-analysis · cited 63 times · open access
PMID 20825643 · DOI 10.1186/1477-7827-8-107 · Reviews and meta-analyses
- Effectiveness and Safety of Postoperative Medical Treatments Following Fertility-Preserving Surgery for Endometriosis: A Network Meta-Analysis.
BJOG : an international journal of obstetrics and gynaecology · September 29, 2025 · Systematic review · cited 3 times
PMID 41017486 · DOI 10.1111/1471-0528.70016 · Reviews and meta-analyses
- Are all gonadotrophin-releasing hormone agonists equivalent for the treatment of prostate cancer? A systematic review.
BJU international · May 8, 2018 · Systematic review · cited 34 times
PMID 29438592 · DOI 10.1111/bju.14168 · Reviews and meta-analyses
- Degarelix for Treating Advanced Hormone-Dependent Prostate Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
PharmacoEconomics · July 1, 2017 · Systematic review · cited 16 times
PMID 27943135 · DOI 10.1007/s40273-016-0481-1 · Reviews and meta-analyses
- Luteinising hormone releasing hormone (LHRH) agonists for the treatment of relapsed epithelial ovarian cancer.
The Cochrane database of systematic reviews · June 29, 2016 · Systematic review · cited 9 times · open access
PMID 27356090 · DOI 10.1002/14651858.cd011322.pub2 · Reviews and meta-analyses
- Pharmacotherapy of paraphilias with long-acting agonists of luteinizing hormone-releasing hormone: a systematic review.
The Journal of clinical psychiatry · August 1, 2003 · Systematic review · cited 134 times
PMID 12927003 · DOI 10.4088/jcp.v64n0806 · Reviews and meta-analyses
- The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy.
Human reproduction (Oxford, England) · September 25, 2026 · Randomized controlled trial · cited 0 times
PMID 42786378 · DOI 10.1093/humrep/deag142 · Human clinical research
Most cited
By OpenAlex citation count. Citations measure attention, not quality or correctness.
- Tumor growth inhibition in patients with prostatic carcinoma treated with luteinizing hormone-releasing hormone agonists.
Proceedings of the National Academy of Sciences of the United States of America · March 1, 1982 · Other clinical trial · cited 368 times · open access
PMID 6461861 · DOI 10.1073/pnas.79.5.1658 · Human clinical research
- Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial.
JAMA · July 1, 2011 · Randomized controlled trial · cited 351 times
PMID 21771987 · DOI 10.1001/jama.2011.991 · Human clinical research
- Endocrine profiles after triggering of final oocyte maturation with GnRH agonist after cotreatment with the GnRH antagonist ganirelix during ovarian hyperstimulation for in vitro fertilization.
The Journal of clinical endocrinology and metabolism · February 1, 2002 · Randomized controlled trial · cited 343 times · open access
PMID 11836309 · DOI 10.1210/jcem.87.2.8197 · Human clinical research
- Adjuvant radiotherapy versus early salvage radiotherapy plus short-term androgen deprivation therapy in men with localised prostate cancer after radical prostatectomy (GETUG-AFU 17): a randomised, phase 3 trial.
The Lancet. Oncology · October 1, 2020 · Randomized controlled trial · cited 329 times · open access
PMID 33002438 · DOI 10.1016/s1470-2045(20)30454-x · Human clinical research
- A lower ongoing pregnancy rate can be expected when GnRH agonist is used for triggering final oocyte maturation instead of HCG in patients undergoing IVF with GnRH antagonists.
Human reproduction (Oxford, England) · June 24, 2005 · Randomized controlled trial · cited 322 times · open access
PMID 15979994 · DOI 10.1093/humrep/dei150 · Human clinical research
Latest publications
- Comparison of cardiovascular events in patients with metastatic hormone sensitive prostate cancer treated with LHRH agonists to LHRH antagonists in the US: A retrospective cohort study.
Urologic oncology · October 18, 2026 · Observational human study · cited 0 times
PMID 42892580 · DOI 10.1016/j.urolonc.2026.09.012 · Human clinical research
- Is there a difference in ovarian hyperstimulation syndrome rates in freeze-all treatment cycles in high-risk patients treated with different GnRH agonist triggers?
Human fertility (Cambridge, England) · October 5, 2026 · Observational human study · cited 0 times · open access
PMID 42831293 · DOI 10.1080/14647273.2026.2733078 · Human clinical research
- The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy.
Human reproduction (Oxford, England) · September 25, 2026 · Randomized controlled trial · cited 0 times
PMID 42786378 · DOI 10.1093/humrep/deag142 · Human clinical research
- Evaluation of triplet therapy combined with robot-assisted cytoreductive prostatectomy for high-volume metastatic prostate cancer: a multicentre randomised controlled trial protocol.
BJU international · August 14, 2026 · Observational human study · cited 2 times · open access
PMID 42598911 · DOI 10.1111/bju.70421 · Human clinical research
- Pubertal Triptorelin Exposure Alters Hypothalamic Reproductive-Metabolic Integration in a Sex-Specific Manner.
Biology · August 12, 2026 · Animal study · cited 0 times · open access
PMID 42651681 · DOI 10.3390/biology15161376 · Animal studies
- Development of a parsimonious predictive model for height gain outcome in children with central precocious puberty following gonadotropin-releasing hormone agonist therapy.
Translational pediatrics · July 27, 2026 · Observational human study · cited 0 times · open access
PMID 42592010 · DOI 10.21037/tp-2026-0254 · Human clinical research
- Central Precocious Puberty and Sjogren-Larsson Syndrome in a Child: A Rare Case Report.
Clinical, cosmetic and investigational dermatology · July 21, 2026 · Case report · cited 0 times · open access
PMID 42502351 · DOI 10.2147/ccid.s594107 · Human clinical research
- Efficacy of 24-weekly vs 12-weekly decapeptyl SR treatment in central precocious puberty: a UK multicentre retrospective cohort study.
The Journal of clinical endocrinology and metabolism · July 1, 2026 · Observational human study · cited 1 times · open access
PMID 41793064 · DOI 10.1210/clinem/dgag096 · Human clinical research
- In vitro fertilization-frozen embryo transfer in a patient with gonadotroph adenoma: Exacerbation of ovarian hyperstimulation by triptorelin: a case report.
Journal of medical case reports · June 25, 2026 · Case report · cited 0 times · open access
PMID 42351311 · DOI 10.1186/s13256-026-06230-5 · Human clinical research
- Sterile abscesses during GnRH agonist therapy for central precocious puberty: a case series and literature review.
Journal of pediatric endocrinology & metabolism : JPEM · June 24, 2026 · Case report · cited 0 times · open access
PMID 42333572 · DOI 10.1515/jpem-2026-0250 · Human clinical research
How this is counted
PubMed records matched by the names below, counted when the peptide is in the title, indexed by MeSH, or confirmed from the abstract. The exact query can be rerun on Europe PMC. Methodology
Search terms: Arvekap; Decapeptyl; Diferelin; Moapar; Trellasar; Trelstar; Triptodur; Triptorelin; Triptoreline
((TITLE_ABS:"Arvekap" OR CHEM:"Arvekap") OR (TITLE_ABS:"Decapeptyl" OR CHEM:"Decapeptyl") OR (TITLE_ABS:"Diferelin" OR CHEM:"Diferelin") OR (TITLE_ABS:"Moapar" OR CHEM:"Moapar") OR (TITLE_ABS:"Trellasar" OR CHEM:"Trellasar") OR (TITLE_ABS:"Trelstar" OR CHEM:"Trelstar") OR (TITLE_ABS:"Triptodur" OR CHEM:"Triptodur") OR (TITLE_ABS:"Triptorelin" OR CHEM:"Triptorelin") OR (TITLE_ABS:"Triptoreline" OR CHEM:"Triptoreline")) AND SRC:MED
Cite this page
Peptide Library. (2026, November 2). Triptorelin research statistics (Version weekly-2026-11-01) [Statistic]. Peptide Library. https://bestpeptidecalculator.app/research/peptides/triptorelin